Nucleic acid therapeutics have surfaced as hopeful possibilities for cancer treatment, including immunotherapy. The growing number of approved nucleic acid therapeutics by the FDA displays their potential to treat diseases by attacking their genetic blueprints.
A discussion of both the promises and perils of artificial intelligence in cervical cancer, brain cancer, and lung cancer treatment. A fast-growing field that promises many scientific breakthroughs in future.
In 2018 Isabelle Carnell-Holdaway a cystic fibrosis sufferer was put in ICU after an aggressive infection of Mycobacterium abscessus, a relative of tuberculosis, spread to her liver putting it at risk of failure. With no new classes of antibiotics discovered and available for routine treatment since the 1980s, she was left with a 1% chance of survival. However in under two years, Isabelle went from receiving end-of-life care to preparing to sit her A-levels and learning to drive. It had taken an experimental bacterio-phage therapy treatment instead of antibiotics to save the life of a girl with a seemingly untreatable bacterial infection. This articles will take a look at a few of the factors which made the discovery of an antibiotic that could have treated Isabelle so difficult.
A unique discovery with a motto to attempt to replace blood transfusions in emergencies, to reduce the high risk of contaminated blood products, to prevent the shortage of blood due to lack of refrigeration or inconvenience to find matching blood types.
In this article I share a very important story of a man who revolutionised neuroscience by losing his own memory. While patient H.M may have forgotten many things in his lifetime, he is an identity that we cannot allow ourselves to forget as he gifted us his own memory.
Traumatic brain injuries are quite common in the US and cause a multitude of neurological conditions. A research team in Ohio discovered two possible treatments for traumatic brain injury and preventing Alzheimer’s disease as well.
This article explores teen mental health, common barriers that make treatment inaccessible, and the way music may be able to help teens in ways many wouldn’t expect.
Replicative Crisis: Mapping Cellular Fates and Identifying Determinants between Cell Survival and Death
In order to divide indefinitely, most cancerous cells activate the enzyme telomerase, which elongates telomeres. To express telomerase, cells typically survive a state known as replicative crisis. This work explores two areas critical to understanding crisis-related mechanisms: the generation of chromosomal aberrations and cytosolic DNA species during crisis and determinants of cell death versus survival during crisis. Understanding these domains is critical to understanding the process of cancer cell immortalization.
For centuries, scientists have pondered about the human body and the structures that make us who we are. In recent decades, advances in genetics have helped us understand more about the human genome and the processes by which we are able to live.
Smart Inhalers: an advanced form of inhalers with digital connection for effective respiratory management, reducing the chances of human errors due to manual usage.
Parkinson’s disease is a progressive central nervous system disorder that affects movement. Symptoms start gradually, ranging from a barely noticeable tremor in just one hand to difficulty controlling eye movements.
Evolution can be defined as the biological process by which the physical characteristics of creatures change over time, new types of creatures develop, and others disappear. With the recent coronavirus pandemic it’s very easy to regard viruses as the enemy of evolution: an arm’s race between a host and a pathogen. This article will explore aspects of human evolution that blur this dichotomy. More specifically how viruses influenced the development of the placenta, the brain and the immune system.
Today, sexuality is a broad spectrum. Learn more about how intersexuality and it’s social implications in both our history and in modern society today.
When placed in a social situation, we go through a series of psychological steps that determine how we perceive and react to what is going on. This process varies from person to person, and is the reason why social interactions can be so unpredictable!
There has been a lot of controversy regarding the COVID-19 vaccine development and many challenges still lie ahead despite the fast-paced rollout of various candidates. In this article I explore the way in which this extreme development has occurred due to the pressure and competitive atmosphere we are presently in, as we face a rat race with each nation striving for their own success. This individualised approach is failing to truly achieve the global effort we need in stamping out this pandemic.
In the age of modern medicine, antibiotics are prescribed regularly. Antibiotics are helpful in preventing harmful conditions and have reduced fatalities by a large number. Unfortunately, a new problem known as antibiotic resistance is emerging as bacteria becomes resistant to antibiotics. Why is antibiotic resistance growing, and how can it be stopped?
The metabolic syndrome is estimated to be present in 47 million Americans. This article discusses the effects of various exercise forms on metabolism and levels of irisin in the female body.
Drug costs are a prominent issue in American healthcare. To investigate health care reform, one must examine the depth of the issue and what can be done. Americans pay higher drug costs than the rest of the world, despite their higher wages and while they also use newer and stronger drugs, some claim that the US is shouldering the burden for drug innovation.
Hours and hours of mindless scrolling does not happen out of nowhere. In our brains, we derive pleasure from the dopamine reward system. As we indulge in social media, this system gets activated and reinforces our behavior to keep us addicted.
A clinical entity with a resemblance of stars on a clear night having calcium lipid complexes being suspended throughout the vitreous collagen fibrils.
Regenerative medicine might be the key to the future..or not. With more experiments and discoveries each day, perhaps it’ll be a pivotal advancement.
This article covers the current progress of genetic editing, and the future of ‘baby-making” or “designer babies”. It also provides an insight into the ethical dilemma and unavoidable exploitation that accompanies the medical advantages of advancement of genetic engineering.
A year into the global pandemic, more public spaces are re-opening, even when the public remains vulnerable to COVID-19 transmissions. While vaccination and herd immunity remains to be the best approach to handle COVID-19, there are fad products booming in the market, which often promote themselves as the virus end-all-be-all product. But exactly how accurate are these marketing schemes and strategies?
Memory is a complex process that makes us who we are. We are a combination of our memory, namely our past experiences. Obviously, our memory isn’t perfect- how many times have you forgotten your keys someplace? Why do we forget things, and how does the process of memory work?
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of some of the most widely prescribed analgesics in the world. This article takes a look at NSAIDs’ mechanism of action and how this is linked to their side effects.
Exploring the causes and effects of asphyxiation and how the cardiothoracic surgeon, Professor Stephen Westaby, revolutionised treatment.
Narcolepsy is a rare chronic sleeping disorder that affects 1 in 2,000 people. This sleeping disorder can affect one lives in various dangerous ways. Those who suffer from narcolepsy find an urge to constantly fall asleep and this could lead to dangerous scenarios like falling asleep while doing normal activities like driving.
Medulloblastoma is a common form of cancer among children. The research team at St. Jude Children’s Hospital sought to find out why one-third of children relapse.
Some minds are so exceptional they completely change the world. Although the reasonings behind the abilities of these minds are not entirely founded, study and research can help to unfold it all. One of the most remarkable minds belongs to one of the greatest physicists of all time. An insight into the brain of the genius scientist, Albert Einstein.
As medical research continues to advance so does our understanding of gene editing, DNA, and human disease. But what are some of the implications of this advancement?
COVID-19 has impacted the world as high numbers of deaths and quarantine has consumed every individual. However, there may be hope as a new breakthrough is expected to bring a great change.
The brain is the most crucial organ in our body, controlling all the functions of the body and processing all the information it receives. Sometimes, epileptics have excessively damaging seizures that can damage the entire brain. In this case, removing parts of the brain is actually a solution: hemispherectomy!
A reflection on the findings, benefits, and dilemma of CRISPR.
The cell cycle is a process most cells go through that ultimately results in a cell dividing into two daughter cells. Although it may sound like a relatively simple process, every step of the process is very complex.
Why are mice so commonly used in biomedical research? Turns out that they are near ideal animal models for more reasons than one.
The research team at Geisinger found that elders carrying a variant of the NOTCH3 gene are at a significantly higher risk of stroke.
Autophagy is a natural process in which the human body destroys viruses and recycles damaged cells. Dr. Xiaonan Dong sought to find precisely which genes were responsible for destroying viruses in order to improve medicine.
Viruses are microscopic organisms, smaller than bacteria, that are only capable of reproducing in a host. With viruses being so different, the question arises: how did they come to be in the first place? Did they evolve from another organism?
Our modern diet is filled with an overwhelming amount of sugar, yet we still we find ourselves craving more and more of this sweet substance. Why does sugar have such an influential role in our body, and what are the consequences of consuming too much sugar?
One common misconception about color blindness is that all color blind people see through a black and white lens. While this is true in some rare cases, most experience a different kind of color blindness.
Eyes are touted as being the window to the soul and now it appears that science has helped that back it up. Learn more about eye colors and their personality traits!
Introduction A report published by the Health Resources and Services Administration (HRSA) identified a scarcity of behavioral health professionals as the primary barrier to meeting the national demand for mental health services. In the United States (U.S.), one in five people have some form of psychological disorder (Weiner, 2018). Moreover, as the demand for psychiatrists […]
Fentanyl has become one of the most valuable drugs for pain treatment throughout the world. Since its creation, fentanyl has been administered in a number of ways, including patches and sprays. Learn more about the studies, uses, and developments of this drug!
When talking about maintaining a youthful look, there are many things that can be done to stop the aging process, one of which is Botox treatment.
Nowadays, we spend many hours inside on our devices. Unfortunately, this exposes us to great amounts of blue light. Explore more about the various affects of blue light and the steps that can be taken to reduce blue light exposure.
While people often view medicine in the form of prescriptions and surgeries, there are often activities to prevent or mitigate health issues. Tai chi is a martial art that is typically thought to only be performed by seniors, but people of all ages can practice tai chi and improve their overall health.
Since the dawn of history, mankind has been on the search for signs of life outside of Earth. Until recently, in the search for answers to life outside of Earth, Venus was largely overlooked, but a fascinating, recent finding could unleash and spark future studies on our neighboring planet.
Recent research on genetic heart disease has revealed information regarding heart failure. A newly discovered gene mutant known as RBM20 affects the way dilated cardiomyopathy is connected to heart failure.
An overview of technological connection with health care to overcome the challenges of the medicine and healthcare industry leading to various developments.
Placebos are drugs or treatments that have no therapeutic value. Despite this, they have shaped modern clinical trials, as well as stirred controversy, all while providing hope for future treatments capitalizing on its beneficial effects.
Bromelain is an aqueous enzyme extract obtained from both the stem and fruit of the pineapple plant and it’s the cause of why your tongue may become irritated or hurt when eating pineapple. This article will briefly explore bromelain’s uses within treating inflammatory diseases, specifically osteoarthritis.
Microbes are small living creatures. They exist in humans and make up the microbiome. The microbiome was often overlooked, but new research shows that it can influence many systems in your body.
Facial transplants, a composite tissue allotransplantation technique, is a rare and risky solution for quality of life issues. However, a review of three cases has been analyzed to provide insight into the benefits and contraindications.
Cell phones are such a vital part of our everyday lives. Children need technology for school and adults need it for work. Virtually anywhere you go, there is technology present. However, studies show that cell phones can actually be a cause of cancer, and have detrimental effects on the body.
Vaping has been an uprising trend recently, especially amongst teens. However, what is actually in these vapor pens, and what does it mean for the safety of today’s teens?
Viruses are often times characterized as destructive to our bodies. The discovery of the special AAV many years ago has led to the development of an innovative gene therapy used to combat several diseases.
The ketogenic diet, commonly referred to as “keto”, is an increasingly popular recent trend in the dieting world. However, new studies show that this diet doesn’t only help put off a few pounds; it can also be used to help epileptic patients and improve the trajectory of their condition.
Contagious diseases spread by mosquitoes have plagued the Earth for decades. However, new technological advancements in genetic engineering may help put an end to this.
The hardships that many encounter when simply attempting to identify a skin condition is beyond a representation of today’s inequality for people of color.
Artificial organs are becoming a common form of technology that relies on methods such as 3-D printing and stem cell implementation. While these organs may seem ideal to patients in need, taking a deeper look into these life-savers reveals a much more complex reality.
An insight into the future technology where machines will emulate human intelligence with more preciseness in the diagnosis of the diseases, thus proving to be a helping hand for doctors and other health care professionals for better treatment and outcomes.
Plastic surgery is often associated with cosmetic procedures, relating to the elective enhancement or change of one’s body or facial features. However, plastic surgery is not limited to this. Instead, reconstructive surgery is another vital segment.
Scientists attempting to grow human organs themselves are not an entirely new concept; in fact, scientists have been conducting this process for well over a decade, growing human organs ranging from kidneys to skin. Researchers have now been able to grow a mini-brain with neural activity that mirrors a preterm infant.
CRISPR/Cas9 has made a name for itself in the medical field as the steadfast tool for genome editing. However, there are many issues of bioethical concern of genome editing in humans.
A new study has shown that dogs can use their highly evolved sense of smell to pick out blood samples from people with cancer with almost 97 percent accuracy.
Cancer can be characterized as the continual unregulated rapid increase in the number of abnormal cells. The use of mouse model cancer cells serves an utmost significance in the field of research as the causal link to carcinogenesis, the initiation of cancer formation, and cancer genes can be used to test and develop new therapies.
Immuno-engineering represents an attractive avenue for cancer treatment with incredible potential for future advancement. As a field in its infancy, the breadth of current research is naturally limited, yet the advantages of immuno-therapeutic treatment are increasingly clear as larger aggregates of clinical data are collected.
The purpose of this proposal is to establish a systematic method of testing and tracking to prevent another pandemic. This method depends on the creation of a global database and the use of generic viral testing, antigen testing, and data analysis prediction models. Implementing a standard method of testing at various ports of entry will help prevent the recurrence of another pandemic.
The continuous use and often misuse of antibiotics, has resulted in the formation of antibiotic-resistant bacteria carrying resistance genes (Lin, Koskella, & Lin, 2017) which encode proteins that annul the effect of these antibacterial agents. The alarming increase in antibiotic resistance has led to a renewed interest in phage therapy; especially the therapeutic use of phages to treat bacterial infections.
Humans are able to isolate their DNA through a series of different techniques such as using centripetal force and alternating temperatures in order to later use the isolated DNA in a Polymerase Chain Reaction (PCR) experiment. In this article, I am going to discuss how I used my remaining products from my PCR experiment to discover my genotype.
Antimicrobial resistance, or AMR, is when microorganisms change or mutate (change in the base sequence of the DNA) after being exposed to an antimicrobial drug, such as an antibiotic or anti-malaria. This allows the microorganisms to become immune to the effects of the drugs and “superbugs”, such as MRSA, can develop.
Polymerase Chain Reaction, or PCR, is a process that allows an individual to replicate many copies of a precise segment of their DNA through a series of calculated procedures. Ever since it was first invented in 1984 by Dr. Kary Mullis, It has become revolutionary in the science of DNA fingerprinting due to its feasibility to amplify DNA.
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