Heart xenotransplantation: A Story of Progress and Setbacks
Heart xenotransplantation (heart transplant where the donor heart is from an animal) has been a fleeting dream on the horizon for many decades, but with the first pig-to-heart human transplant having been attempted this year, it is time to evaluate the merits and prospects of this procedure and what it means for patients.
Brain Organoids: A Narrative Review of Potential, Limitations and Future
The rapid development of stem cell technology has opened up unprecedented avenues for studying human neurodevelopment, and one of such avenue is the study of brain organoids, or “mini-brains”. How do they work, what can these be used to study and how viable are the models they provide? This article seeks to answer some of these questions.
Monkey Pox: Public Health Response, Reporting and Stigma
What can the public health response to the Monkeypox outbreak in the summer of 2022 teach us about public health?
The Role of Personal Hygiene in Preventing Bacterial Infections
Remember when your mom used to yell at you for not washing your hands before you eat? Or maybe not maintaining good hygiene? Well, she isn’t wrong. So, what is this key role of personal hygiene and how do you implement it?
The Neuroscience Behind Emotions: Exploring The Science Behind Emotions
Emotions are what makes us human. They are what motivate our actions and aid us to communicate with others. Without emotions, nothing would have any sort of meaning. And so, what even are emotions? How do they work? What is their purpose? This article covers the science behind emotions, how they function, and how it influences our daily life.
The Science Behind Déjà Vu
Have you ever looked at something and have had an eerie thought of familiarity? “Wait, I feel like I have already been here before..”, “This is so weird, I swear I met you somewhere..”, or even something as simple as, “I felt like I already bought the groceries for this week.” So, what is this feeling? Will science be able to explain it?
Exploring The Nervous System
The Nervous System is the body’s internal communication system. These sensory cues are interpreted by the brain to understand what is going on outside and inside the body. Without the Nervous System, we would never understand what’s going on.
The Evolution of Sulfonylureas as Hypoglycaemic Drugs Over Time, their Mechanisms and how they Treat Symptoms of Type II Diabetes Mellitus.
This article will explain the chemistry of sulfonylureas, the pharmacology behind them and how they have changed over time to make them more effective in the treatment of type 2 diabetes mellitus.
AI and Moral Status
With the rapid advancements in the intersection between neuroscience and technology, the existence of Artificial General Intelligence has become more a question of when rather than if. Such an entity will lead to questions regarding morality, specifically moral status. This article aims to discuss moral status in Artificial General Intelligence. In the end, it is important for experts to value public opinion when forming their decision.
Music and Medicine
You might have heard of the term music therapy but do you know what it is? Do you know how it works and who it treats?
Efficacy of CAR-T cell Therapy in Patients with Hodgkin lymphoma who Relapse or Experience Primary Refractory Disease
CAR-T cell therapy shows promising results in cancer treatments, however, in terms of treating Hodgkin’s lymphoma it is considered an option when patients relapse or experience primary refractory disease. CAR-T cell therapy is considered a good alternative to regular treatment as the safety is high and, at the same time, it makes many patients respond to treatment.
The Evolution of Sulfonylureas as Hypoglycaemic Drugs Over Time, Their Mechanisms and how they Treat Symptoms of Type II Diabetes Mellitus.
This article will explain the chemistry of sulfonylureas, the pharmacology behind them and how they have changed over time to make them more effective in the treatment of type 2 diabetes mellitus.
Ageing, genetics and Parkinson’s
Nowadays vast amounts of misinformation surface the internet, constructing controversies. Within the same spectrum, healthcare professionals seek to support or contradict the argument, through evidence-based judgement. Likewise, contributing factors of Parkinson’s disease stand firm ground between the evaluation of healthcare professionals across the platform. The Parkison’s debate, distinctly separates itself into three categories, which will be discussed in this article.
Anxiety Disorder: Exploring The Reality Behind Having Anxiety
Anxiety. A term that is used so frequently that it lost its meaning. This article covers the biology of the illness, how it is processed in the brain, its influences on individuals and the various diagnosis and treatment.
Diabetes and Periodontal Disease
This article looks at the relationship between two diseases: Periodontal disease and Diabetes. Is there just a correlation or has a causal relationship been justified?
The Negative Influence of Coronary Heart Disease on the World
Whether or not a country is developed is irrelevant, as coronary heart disease is a prominent problem in both developing and developed countries.
Is Communication Important in the NHS?
Throughout the development of the NHS, since 1948, paramount structural alterations have proceeded, due to the absence of a the utmost important element: communication.
The Neurobiology and Superficial Traits of Psychopathy
This article examines the neurobiology and traits of psychopathy, through case studies and the discussion of diagnosis.
Mendelian Laws: How Does a Better Understanding of These Principles Help With the Diagnosis and Treatment of Complex Diseases?
“Mendelian diseases” are single-gene diseases that are caused by mutant genes that interfere with the specific function and phenotype shown in a genome [3]. These single-gene conditions can be readily modelled using Mendelian laws of inheritance and our understanding of these conditions is generally more complete.
Refeeding Syndrome – A Dangerous Complication of Anorexia Nervosa Treatment
Refeeding syndrome is one of the most dangerous and known complications from anorexia nervosa. This potentially lethal condition does not result in mortality itself – it is the electrolyte disturbances that occur secondary, resulting in organ failure and sometimes death.
Dostarlimab: Hope or Hype?
One recent form of immunotherapy, a drug called Dostarlimab, has taken the medical world by storm after a small study reported a 100% complete clinical response.
ADHD: Over Diagnosed or Loosely Defined?
Accusations of ADHD’s overdiagnosis have been on a rise in recent years, as have diagnosed cases of ADHD. In 1997, the parent-reported percent of children with an ADHD diagnosis in a National Health Institute survey was just under 6%. Ten years later, this figure had risen to 10% [2].
The Brain: How does it actually work?
The brain, arguably it’s the human body’s most unexplored organ. That’s because it’s a very complicated organ that controls every possible aspect of our life. The way we think, how we feel, touch, see, and even something as simple as breathing, letting us stay alive every second. The brain is made of about 60% fat […]
Is communication important in the NHS?
The NHS encounters challenges constantly, the importance of revisiting failures and resolutions of prior inquiries in the NHS is paramount.
CRISPR Gene Editing: From novel treatment to reality
With the endless developments in genetic engineering and the discovery of CRISPR-Cas9 gene editing lately, it is difficult not to wonder if the creation of super mutants in our reality is possible. This article will explain how these so-called “superhumans” could already be walking the earth much sooner than expected, and explore the seemingly endless possibilities of this new gene-editing method.
What causes stuttering, how it is treated and how it may affect people
Background Stuttering, also known as speech dysfluency, is a condition that involves involuntary verbal expressions. Often stuttering is characterised by repetitions of words, letters or sounds, however, it may also be prolongations of the latter. In other instances speech dysfluency is demonstrated through tension in one’s speech while pronouncing words. A person who stutters may […]
Behind the Controversial and Forbidden Technique of Gene Editing
A deep dive into the recent innovation of CRISPR gene editing. The reasons behind its controversy and why it’s banned from nearly every nation. Answering the very questions behind the ethicality of this new technique.
When is the Next Pandemic after COVID coming? Sorry, it’s already here.
Five years ago, Bill Gates warned the world about an impending global pandemic during a TED Talk titled “The next outbreak? We’re not ready”. So, if Gates was right the first time, when can we expect the next pandemic? This article will address the implications of a mental health crisis already upon us and address the social stigmas associated with such illnesses.
Antibiotic Resistance: The Quiet Crisis
Introduction Since the inception of the first penicillin drug in 1928 by Alexander Fleming, antibiotics have systematically changed and revolutionized the field of medicine. These antibiotics drugs or antimicrobial substances are widely used throughout medical treatment to prevent infections by inhibiting the growth and survival of bacteria. However, as the use of antibiotics continues to […]
Arya Bhatt: Water Fluoridation
Water fluoridation is the adjustment of fluoride ions within the public water supply. Through extensive research, water fluoridation has been evidenced to improve the oral health of the wider population, especially in areas of lower deprivation where levels of oral health are seen to be much worse. This article will look into how water fluoridation […]
Magic Mushrooms: A Revolutionary Clinical Treatment
Introduction Psychedelics, additionally known as hallucinogens, are a class of drugs that are hallucinogenic, and can cause changes in perception, mood, and cognitive processes when they are taken by individuals (1). The most well-known psychedelic is psilocybin – the key compound in magic mushrooms, which are prominent for the hallucinogenic effects they induce when ingested […]
Poxes and Vaccinations
This article discusses vaccinations through the lens of poxes, namely the small poxes that inspired Edward Jenner and the rapidly rising cases of monkey pox around the world. What are poxes? Poxes have a large double-strand DNA genome and an oval shape. Animals are the major carriers of the virus, and they also cause it. […]
What would we do without anaesthetics
General anaesthesia(scientifically known as narcosis) is the act of putting a patient to sleep, which induces complete unconsciousness. Its function is to prevent the patient’s awareness during surgery by suppressing reflex activity, which causes surgical interventions to be easier, and ultimately allows comfort to the patient. The development of anaesthetics has a unique and fascinating […]
Is stem cell treatment a viable option in restorative dentistry?
By: Arya Bhatt Stem cells have been at the forefront of scientific research and have been an invaluable tool in the scientific field due to their fantastic properties. Their ability to divide over and over again to produce many new cells whilst specialising in the different types of cells the body requires has enabled researchers […]
Machine Learning in Medicine – The Next Revolutionary Technology?
Machine Learning is increasingly becoming utilised in various sectors from engineering to psychology, and new successful developments of machine learning indicate that these technologies could be beneficial in medical settings. However, the viability of these technologies is questioned, given the ethical and logistical difficulties in medicine.
Current Difficulties in Medical Diagnostics
Medical diagnostics allow medical professionals to chart medical symptoms to other data and produce diagnoses and outcomes. However, difficulties in this medical field can result in diagnostic errors, causing detrimental costs to patients and healthcare systems.
Medicinal Cannabis
This article concludes the history, uses of medicinal cannabis and some misconceptions in cannabis in general.
A Man Who Received a Heart Transplant from a Pig
This article discusses the use of genetically modified pig hearts for heart transplants and highlights the case of David Bennet, a pig heart recipient.
Brain Reading Technology
Reading minds is not as far fetched as it seemed to be in the past. With much research and technology, verbalizing a person’s thought process appears possible.
Thalidomide: Horrifying Tragedy of the Past, Auspicious Treatment of the Future
An article detailing the medical travesty that was thalidomide, and yet the promising nature of it for the future.
Nanoparticles in Dentistry
This article gives a short overview into how nanoparticles within fields of dentistry can be utilised to exemplify patient treatment and improve patient satisfaction.
Should Consent be Needed for Organ Procurement?: A Discussion
A discussion about organ procurement in relation to the pressure for suitable organ donations and the ethics involved.
Should the NHS Allocate Funding for Somatic Gene Therapy?: A Discussion
An article evaluating whether the NHS should allocate funding for somatic gene therapy and the differences between somatic and germline therapies.
Emerging Treatment Options for Triple-Negative Breast Cancer
Here we review current standard therapies available, second-line therapies, and other emerging treatments for Triple-Negative Breast Cancer (TNBC) with an emphasis on risks associated with specific patient attributes.
Importance of Oral Health
This article gives an introduction to the importance of oral health
for a better overall body health and how countries all over the world are attempting to better the oral health of the general population.
BRCA2’s Relation with Aldehydes Leads to a Higher Risk of Developing Prostate Cancer Than BRCA1
This retrospective analysis research paper discusses why the difference between the responses of aldehyde exposure from patients with a heterozygous germline mutation in BRCA2 and BRCA1 leads to a higher risk of prostate cancer in BRCA2 mutant carriers than BRCA1.
Why should we not underestimate the role of epigenetics in treating cancer?
This article discusses how the discovery of epigenetic mechanisms has significantly added to our understanding on genetics. It also explains how this knowledge can be used to produce drugs which counteract these mechansisms.
Omicron Virus: Another COVID Variant of Concern
An overview of the current variant of SARS-CoV-2 virus leading to the continuity of the current pandemic situation.
Risk Factors of Alzheimer’s Disease and the Impact of Socioeconomic Status: A Review
Abstract While the etiology of Alzheimer’s Disease (AD) is unknown, scientists have identified many risk factors, which will be examined in this review (Watwood, 2011). These risk factors include age, genetics, cardiovascular health, diet, sleep, mental health, education, and socioeconomic status (SES). In AD, a protein called beta-amyloid accumulates slowly over time, resulting in the risk […]
Impact of Obstetrics and Gynecology upon Modern Society
An article exploring the importance of Obstetrics and Gynecology in the modern day and how its development has improved life for women globally.
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Youth Medical Journal 